Butabarbital decreases results of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of CYP3A4 inducers may lessen sufentanil concentrations and efficacy, possibly precipitating withdrawal syndrome in sufferers which have created Bodily dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers... https://andersonl009flv9.activablog.com/profile