There is a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors inside the dorsal horn to minimize afferent soreness transmission and make analgesia. As a result, drugs like clonidine that focus on alpha-two receptors can affect the transmission of discomfort. : linked to, served https://clinti035jha5.homewikia.com/user