Not all individuals with CLL need therapy. Despite all recent innovations, the iwCLL continue to suggests watchful observation for patients with asymptomatic disease.86 This suggestion relies on at least two randomized trials comparing observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Equally trials concluded that early therapy https://landenksblr.dm-blog.com/32523694/not-known-details-about-situs-judi-mbl77